The long isoform uncoupling protein-3 (UCP3L) in human energy homeostasis

Authors
Chung, WK Luke, A Cooper, RS Rotini, C Vidal-Puig, A Rosenbaum, M Gordon, D Leal, SM Caprio, S Goldsmith, R Andreu, AL Bruno, C DiMauro, S Heo, M Lowe, WL Lowell, BB Allison, DB Leibel, RL
Citation
Wk. Chung et al., The long isoform uncoupling protein-3 (UCP3L) in human energy homeostasis, INT J OBES, 23, 1999, pp. S49-S50
Citations number
14
Categorie Soggetti
Endocrynology, Metabolism & Nutrition","Endocrinology, Nutrition & Metabolism
Journal title
INTERNATIONAL JOURNAL OF OBESITY
ISSN journal
03070565 → ACNP
Volume
23
Year of publication
1999
Supplement
6
Pages
S49 - S50
Database
ISI
SICI code
0307-0565(199906)23:<S49:TLIUP(>2.0.ZU;2-G
Abstract
The biological role(s) proposed for UCP3 in energy homeostasis have been ba sed primarily upon amino acid sequence homology to UCP1. Spontaneous mutati ons of UCP3> have been described in humans, but not in rodents. The functio nal consequences-or lack thereof-of these mutations in humans will be of gr eat importance in elucidating the biology of this protein. The results of t wo such studies are summarized here.