INDOCYANINE GREEN ANGIOGRAPHY IN CHOROIDAL OSTEOMA

Background: Choreidal osteoma is a rare choroidal tumor: knowledge of its indocyanine green characteristics is limited, Methods: The fundus photographs and the fluorescein and indocyanine green angiograms of th ree patients were reviewed, Each patient was examined at least twice w ith a follow-up varying from 10 to 60 months. Results: Late-phase fluo rescein angiograms allow assessment of the extension of the osteoma as it is variably hyperfluorescent due to tumor staining combined with a variable degree of overlying retinal pigment epithelial changes. The hypofluorescent area observed in the early phase of the indocyanine gr een angiogram corresponds with the extent of the osteoma but the borde rs may be difficult to demarcate, In the late phase of the indocyanine green angiogram, hypofluorescence due to choriocapillaris loss and hy perfluorescence due to leakage from abnormal choroidal vessels are com bined, infrared angiography highlights abnormal choroidal vessels and vascular spiders present on the tumor surface. It is difficult to diff erentiate these choroidal vascular anomalies from subretinal neovascul arization, Conclusion: We find no homogeneous pattern either on fluore scein or on infrared angiography. The findings may change with fellow- up, indicating changes within the tumor or the surrounding tissue that are still poorly understood.