Ischemic stroke and migraine in childhood: Coincidence or causal relation?

Although migraine is an accepted cause of cerebral infarction in adults, th is association is less well recognized in children. We present two children with migraine and cerebral infarction, which we regard as migrainous strok e, though neither patient fulfills all criteria of the International Headac he Society for the diagnosis of migrainous infarction. Review of the litera ture concerning examples of migraine-associated stroke in childhood suggest s that these criteria are too restrictive to comprise the majority of migra inous strokes, especially in this age group.