Qualitative and quantitative micellar electrokinetic chromatography of kavalactones from dry extracts of Piper methysticum Forst. and commercial drugs

Citation
M. Lechtenberg et al., Qualitative and quantitative micellar electrokinetic chromatography of kavalactones from dry extracts of Piper methysticum Forst. and commercial drugs, J CHROMAT A, 848(1-2), 1999, pp. 457-464
Citations number
20
Categorie Soggetti
Chemistry & Analysis","Spectroscopy /Instrumentation/Analytical Sciences
Journal title
Volume
848
Issue
1-2
Year of publication
1999
Pages
457 - 464
Database
ISI
SICI code
Abstract
A rapid micellar electrokinetic chromatography method with diode-array dete ction has been developed for the identification and quantitative determinat ion of the therapeutically important styrylpyrones from Piper methysticum e xtracts and commercial drugs. Using fused-silica capillaries with a berate buffer containing sodium-taurodeoxycholic acid and beta-cyclodextrin kavain , dihydrokavain, methysticin, dihydromethysticin, yangonin and demethoxyyan gonin were fully separated and quantified within 15 min with 4-hydroxybenzo ic acid methyl ester as I.S. (C) 1999 Elsevier Science B.V. All rights rese rved.