A facile synthesis of 1-H-2,2-difluorovinylphosphorus compounds from 2,2,2-trifluoroethyl trifluoromethanesulfonate and substitutions of their vinylic fluorines

2,2-Difluorovinylphosphine as well as its oxide and borane-complex are synt hesized in high yields via the P-trifluoroethylation of lithium diphenylpho sphide with 2,2,2-trifluoroethyl trifluoromethanesulfonate, followed by deh ydrofluorination with potassium tert-butoxide. The reactions of 2,2-difluor ovinylphosphine oxide and borane-complex with hydride, S- and N-nucleophile s proceed via an addition-elimination process to afford mono- or nonfluorov inylphosphorus compounds and carbamoylmethylphosphine oxides. (C) 1999 Else vier Science S.A. All rights reserved.