Synthesis and spectral properties of 2,3-dihydro-2-[(o- and p-substituted)anilinylidene]-1H-4-(p-methylphenyl)-7[(o- and p-methyl)phenoxy]-1,5-benzodiazepines
Ec. Cortes et Mps. Bravo, Synthesis and spectral properties of 2,3-dihydro-2-[(o- and p-substituted)anilinylidene]-1H-4-(p-methylphenyl)-7[(o- and p-methyl)phenoxy]-1,5-benzodiazepines, J HETERO CH, 36(3), 1999, pp. 611-615
A series of twelve new 2,3-dibydro-2-[(o- and p-substituted)anilinylidene]-
1H-4-(p-methylphenyl)-7-[(o- and p-methyl)phenoxy]-1,5-benzodiazepines, whi
ch have potentially useful pharmacological proper ties, has been synthesize
d by condensing the 3,3-dimercapto-1-(p-methylphenyl)-2-propen-1-one with 3
,4-diaminophenyl-R-phenyl ethers. Subsequently the 1H-1,5-benzodiazepine-2-
thiones obtained were treated with the (o- and p-substituted)aniline. The s
tructure of all products was corroborated by ir, H-1 nmr, C-13 nmr and ms.