Ectopic ACTH syndrome due to thymic carcinoid tumor in a girl

Citation
Kl. Lin et al., Ectopic ACTH syndrome due to thymic carcinoid tumor in a girl, J PED END M, 12(4), 1999, pp. 573-578
Citations number
17
Categorie Soggetti
Endocrinology, Nutrition & Metabolism
Journal title
JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
ISSN journal
0334018X → ACNP
Volume
12
Issue
4
Year of publication
1999
Pages
573 - 578
Database
ISI
SICI code
0334-018X(199907/08)12:4<573:EASDTT>2.0.ZU;2-5
Abstract
An 8 year-old girl had a cushingoid appearance for six months. Hormone stud y showed extremely high serum levels of cortisol (>60 mu g/dl) and adrenoco rticotropic hormone (930 pg/ml), Initial chest X-ray showed nothing unusual , but a technetium-99mm MIBI scan showed an accumulation lesion in the left upper chest cavity, Chest magnetic resonance imaging demonstrated that the mass was in the superior anterior mediastinum, She had complete removal of the tumor with partial thymectomy. The pathology revealed a thymic carcino id tumor, Carcinoid tumors of the thymus are extremely rare in children and they usually present with Gushing's syndrome. To our knowledge, this is th e youngest patient who has ever been reported with this disease.