Preparation of desymmetrised meso-tartrate derivatives - synthesis and utility of (R ',R ',R,S)-2,3-butane diacetal protected dimethyl tartrate

Authors
Dixon, DJ Foster, AC Ley, SV Reynolds, DJ
Citation
Dj. Dixon et al., Preparation of desymmetrised meso-tartrate derivatives - synthesis and utility of (R ',R ',R,S)-2,3-butane diacetal protected dimethyl tartrate, J CHEM S P1, (12), 1999, pp. 1631-1633
Citations number
27
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
ISSN journal
0300922X → ACNP
Issue
12
Year of publication
1999
Pages
1631 - 1633
Database
ISI
SICI code
0300-922X(19990621):12<1631:PODMD->2.0.ZU;2-K
Abstract
The synthesis of 2,3-butane diacetal protected dimethyl tartrate (R',R',R,S )-1 using a chiral memory protocol and its utility for the preparation of d esymmetrised meso-tartrate derivatives through selective transesterificatio n and aminolysis of the spatially different carboxylate termini is describe d.