Solid state oxidation of 1,4-dihydropyridine to pyridines using phenyliodine(III) bis(trifluoroacetate) or elemental sulfur

Authors
Varma, RS Kumar, D
Citation
Rs. Varma et D. Kumar, Solid state oxidation of 1,4-dihydropyridine to pyridines using phenyliodine(III) bis(trifluoroacetate) or elemental sulfur, J CHEM S P1, (12), 1999, pp. 1755-1757
Citations number
49
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
ISSN journal
0300922X → ACNP
Issue
12
Year of publication
1999
Pages
1755 - 1757
Database
ISI
SICI code
0300-922X(19990621):12<1755:SSOO1T>2.0.ZU;2-A
Abstract
A solventless oxidation of 1,4-dihydropyridines is effected by phenyliodine (III) bis(trifluoroacetate) (PIFA) at room temperature or elemental sulfur under microwave irradiation conditions. Dealkylation at the 4-position in t he cases of ethyl, isopropyl and benzyl substituted dihydropyridine derivat ives with PIFA is circumvented by an alternative general procedure using el emental sulfur which provides pyridines in good yields.