Sd. Carson et al., Expression of the coxsackievirus and adenovirus receptor in cultured humanumbilical vein endothelial cells: Regulation in response to cell density, J VIROLOGY, 73(8), 1999, pp. 7077-7079
Primary cultures of human umbilical vein endothelial cells (HUVEC) express
the human coxsackievirus and adenovirus receptor (HCAR). Whereas HCAR expre
ssion in Beta cells was constant with respect to cell density, HCAR express
ion in HUVEC increased with culture confluence. HCAR expression in HUVEC wa
s not quantitatively altered by infection with coxsackievirus B.