Nigral endothelial dysfunction, homocysteine, and Parkinson's disease

Authors
Muller, T Werne, B Fowler, B Kuhn, W
Citation
T. Muller et al., Nigral endothelial dysfunction, homocysteine, and Parkinson's disease, LANCET, 354(9173), 1999, pp. 126-127
Citations number
5
Categorie Soggetti
General & Internal Medicine","Medical Research General Topics
Journal title
LANCET
ISSN journal
01406736 → ACNP
Volume
354
Issue
9173
Year of publication
1999
Pages
126 - 127
Database
ISI
SICI code
0140-6736(19990710)354:9173<126:NEDHAP>2.0.ZU;2-W
Abstract
We found increased levels of atherosclerosis-inducing homocysteine in parki nsonian patients with long-term application of levodopa compared with previ ously untreated parkinsonian patients and controls. We conclude that antipa rkinsonian treatment with levodopa promotes occurrence of vascular disease in Parkinson's disease.