Intrapartum levels of endogenous glutamate antagonist kynurenic acid in amniotic fluid, umbilical and maternal blood

Authors
Milart, P Urbanska, EM Turski, WA Paszkowski, T Sikorski, R
Citation
P. Milart et al., Intrapartum levels of endogenous glutamate antagonist kynurenic acid in amniotic fluid, umbilical and maternal blood, NEUROSC R C, 24(3), 1999, pp. 173-178
Citations number
9
Categorie Soggetti
Neurosciences & Behavoir
Journal title
NEUROSCIENCE RESEARCH COMMUNICATIONS
ISSN journal
08936609 → ACNP
Volume
24
Issue
3
Year of publication
1999
Pages
173 - 178
Database
ISI
SICI code
0893-6609(199905/06)24:3<173:ILOEGA>2.0.ZU;2-A
Abstract
Our study provides basis for future analyses of endogenous glutamate antago nist kynurenic acid metabolism in the fete-placental unit. The concentratio n of kynurenic acid was found to be higher in amniotic fluid and umbilical cord blood than in respective maternal blood, as revealed in 32 mother-neon ate pairs. Kynurenic acid level in amniotic fluid correlated positively wit h its concentration in umbilical cord blood but not in maternal blood. Kynu renic acid levels in umbilical cord blood and in maternal blood correlated positively with placental weight and relative placental weight.