A novel approach for the synthesis of seco C-nucleoside analogues

Authors
Awad, LF El Ashry, EH
Citation
Lf. Awad et Eh. El Ashry, A novel approach for the synthesis of seco C-nucleoside analogues, NUCLEOS NUC, 18(4-5), 1999, pp. 557-558
Citations number
5
Categorie Soggetti
Biochemistry & Biophysics
Journal title
NUCLEOSIDES & NUCLEOTIDES
ISSN journal
07328311 → ACNP
Volume
18
Issue
4-5
Year of publication
1999
Pages
557 - 558
Database
ISI
SICI code
0732-8311(1999)18:4-5<557:ANAFTS>2.0.ZU;2-J
Abstract
The synthesis of 4-amino-3-(D-gluco- or D-galacto-pentitoi-1.yl)-5-mercapto -1,2,4-triazoles and their conversion to the respective 6-methyl-3-(1,2,3,4 ,5-penta-O-acetyl-pentitol-1-yl)1,2,4-triazolo[3,4-b] 1,3,4-thiadiazoles ha ve been achieved. The vicinal coupling constants were used to deduce the fa vored conformations.