Lithiation-stannylation chemistry of nucleosides

Authors
Tanaka, H Kumamoto, H Shindoh, S Hayakawa, H Kato, K Miyasaka, T
Citation
H. Tanaka et al., Lithiation-stannylation chemistry of nucleosides, NUCLEOS NUC, 18(4-5), 1999, pp. 585-586
Citations number
6
Categorie Soggetti
Biochemistry & Biophysics
Journal title
NUCLEOSIDES & NUCLEOTIDES
ISSN journal
07328311 → ACNP
Volume
18
Issue
4-5
Year of publication
1999
Pages
585 - 586
Database
ISI
SICI code
0732-8311(1999)18:4-5<585:LCON>2.0.ZU;2-Z
Abstract
Two examples of-anionic stannyl migration practically useful for nucleoside synthesis are presented. One involves the migration from the 8- to 2-posit ion of 6-chloropurine derivatives, which provided a new entry to 2-substitu ted purine nucleosides. The other is that from the 6- to 2'-position of 1', 2'-unsaturated uridine. The latter enabled the preparation of a hitheroto u nknown class of nucleoside analogues, 2'-substituted 1',2'-unsaturated urid ines.