Stereospecific synthesis and antiviral activities of beta-L-2 ',3 '-dideoxy-5-chloropyrimidine nucleoside derivatives

Authors
Pierra, C Gosselin, G Sommadossi, JP Faraj, A De Clercq, E Balzarini, J Imbach, JL
Citation
C. Pierra et al., Stereospecific synthesis and antiviral activities of beta-L-2 ',3 '-dideoxy-5-chloropyrimidine nucleoside derivatives, NUCLEOS NUC, 18(4-5), 1999, pp. 643-644
Citations number
7
Categorie Soggetti
Biochemistry & Biophysics
Journal title
NUCLEOSIDES & NUCLEOTIDES
ISSN journal
07328311 → ACNP
Volume
18
Issue
4-5
Year of publication
1999
Pages
643 - 644
Database
ISI
SICI code
0732-8311(1999)18:4-5<643:SSAAAO>2.0.ZU;2-1
Abstract
Several 5-chlorouracil and 5-chlorocytosine beta-L-dideoxynucleosides were stereospecifically synthesized and their activities against human immunodef iciency virus (HIV) and hepatitis B virus (HBV) were examinated in cell cul ture.