Unexpected results in the reaction of 5 '-tosyl TSAO-m(3)t with amines

Authors
Chamorro, C Velazquez, S Jimeno, ML Perez-Perez, MJ Lobaton, E Tunon, V Esteban-Gamboa, A Gago, F De Clercq, E Balzarini, J Camarasa, MJ San-Felix, A
Citation
C. Chamorro et al., Unexpected results in the reaction of 5 '-tosyl TSAO-m(3)t with amines, NUCLEOS NUC, 18(4-5), 1999, pp. 715-716
Citations number
4
Categorie Soggetti
Biochemistry & Biophysics
Journal title
NUCLEOSIDES & NUCLEOTIDES
ISSN journal
07328311 → ACNP
Volume
18
Issue
4-5
Year of publication
1999
Pages
715 - 716
Database
ISI
SICI code
0732-8311(1999)18:4-5<715:URITRO>2.0.ZU;2-0
Abstract
We report our strategies to prepare TSAO compounds carrying at 5'-position groups, such as amines, that may be positively charged at physiological con ditions, unexpectedly, cyclic TSAO-derivatives were obtained. A possible me chanism for the formation of these unexpected compounds is advanced.