Structural studies of 5-ethyl-2 '-deoxyuridine by selective pulse H-1 DPFGSE NOE spectroscopy and PM3 calculations.

Authors
Bailey, LE Garcia-Martin, ML Stender, H Ball, G
Citation
Le. Bailey et al., Structural studies of 5-ethyl-2 '-deoxyuridine by selective pulse H-1 DPFGSE NOE spectroscopy and PM3 calculations., NUCLEOS NUC, 18(4-5), 1999, pp. 1067-1068
Citations number
6
Categorie Soggetti
Biochemistry & Biophysics
Journal title
NUCLEOSIDES & NUCLEOTIDES
ISSN journal
07328311 → ACNP
Volume
18
Issue
4-5
Year of publication
1999
Pages
1067 - 1068
Database
ISI
SICI code
0732-8311(1999)18:4-5<1067:SSO5'B>2.0.ZU;2-9
Abstract
The solution conformation of 5-ethyl-2'-deoxyuridine (EDU) has been calcula ted from the vicinyl proton-proton NMR coupling constants and nuclear Overh auser (NOE) distances using excitation sculpting of selective pulses (Doubl e Pulsed Field Gradient Spin Echo NOE) at 500 MHz and molecular modelling ( PM3) studies.