Synthesis of a new analog of thymidine for in vivo nonradioactive labelingof DNA

Authors
Rodriguez-Tanty, C Perez, R Miranda, J Velez-Castro, H Rosado, A Macias, A Galan, L Higginson-Clarke, D Riveron, AM
Citation
C. Rodriguez-tanty et al., Synthesis of a new analog of thymidine for in vivo nonradioactive labelingof DNA, NUCLEOS NUC, 18(4-5), 1999, pp. 1113-1117
Citations number
15
Categorie Soggetti
Biochemistry & Biophysics
Journal title
NUCLEOSIDES & NUCLEOTIDES
ISSN journal
07328311 → ACNP
Volume
18
Issue
4-5
Year of publication
1999
Pages
1113 - 1117
Database
ISI
SICI code
0732-8311(1999)18:4-5<1113:SOANAO>2.0.ZU;2-O
Abstract
The introduction of 6-(p-bromobenzoylamino)caproyl radical in the methyl gr oup of 2'-O-deoxythymidine is described. In vivo incorporation of this nucl eoside to DNA was determined using a monoclonal antibody that recognized th e radical.