Sf. Egger et al., Corneal wound healing after superficial foreign body injury: Vitamin A anddexpanthenol versus a calf blood extract - A randomized double-blind study, OPHTHALMOLA, 213(4), 1999, pp. 246-249
A prospective randomized double-blind clinical study was performed to inves
tigate corneal wound healing after treatment either with an eye gel contain
ing calf blood extract or an eye ointment containing vitamin A and dexpanth
enol. A total of 54 outpatients were included in this study, all treated fo
r corneal foreign body injury. The size of the corneal lesions was measured
by planimetry on days 0, 1, and on the following days until complete epith
elial healing occurred. Results showed the calf blood extract eye gel to be
statistically more effective in promoting corneal wound healing, especiall
y in patients with wound areas larger than 6 mm(2).