Directed molecular evolution

We propose the existence of a relationship of stereochemical complementarit y between gene sequences that code for interacting components: nucleic acid -nucleic acid, protein-protein and protein-nucleic acid. Such a relationshi p would impose evolutionary constraints on the DNA sequences themselves, th us retaining these sequences and governing the direction of the evolutionar y process. Therefore, we propose that prebiotic, template-directed autocata lytic synthesis of mutally cognate peptides and polynucleotides resulted in their amplification and evolutionary conservation in contemporary prokaryo tic and eukaryotic organisms as a genetic regulatory apparatus. If this pro posal is correct, then the relationships between the sequences in DNA codin g for these interactions constitute a life code of which the genetic code i s only one aspect of the many related interactions encoded in DNA.