Permeability of tympanotomy tubes to ototopical preparations

Myringotomy with tube placement is the most frequently performed otolaryngo logic procedure in the United States, and purulent otorrhea after this proc edure is not uncommon. Believing that ototopical preparations have proved u seful in treating this malady, our group was compelled to examine whether a nd in what quantities these preparations are able to penetrate tympanotomy tubes. To this end, models were constructed and in vitro testing carried ou t with several popular formulations.