W. Joshi et al., A comparison of two concentrations of bupivacaine and adrenaline with and without fentanyl in paediatric inguinal herniorrhaphy, PAEDIATR AN, 9(4), 1999, pp. 317-320
This study was designed to determine whether administration of caudal bupiv
acaine with fentanyl would have any effect on analgesia in paediatric patie
nts undergoing inguinal hemiorrhaphy repair. Fifty-six outpatient paediatri
c patients undergoing inguinal hernia repair were evaluated. Patients recei
ved, in a randomized manner, 1 ml.kg(-1) of either bupivacaine 0.25% or 0.1
25% with or without fentanyl 1 mu g.kg(-1). There was no difference in pain
scores in the hospital, the night of surgery, or 24 h postoperatively nor
was there a difference in the oral analgesics administered between any of t
he groups. There was a higher incidence of vomiting at home in both 0.25% b
upivacaine groups irrespective of the use of fentanyl. The 0.125% bupivacai
ne group had significantly more patients who received intravenous fentanyl
in the PACU than did the other three groups (P<0.001). Increasing the conce
ntration of bupivacaine from 0.125% to 0.25% increased the incidence of pos
toperative vomiting. We recommend that clinicians utilize bupivacaine 0.125
% with 1 mu g.kg(-1) fentanyl as the caudal injectate in paediatric patient
s undergiong inguinal hernia repair.