W. Habre et al., Extrapyramidal side-effects front droperidol mired with morphine for patient-controlled analgesia in two children, PAEDIATR AN, 9(4), 1999, pp. 362-364
We report two cases of extrapyramidal reactions occurring in children follo
wing the use of droperidol in combination with morphine for patient-control
led analgesia (PCA). Symptoms appeared 38 and 27 h, respectively, after com
mencement and after a total dose of 0.14 mg.kg(-1) and 0.17 mg.kg(-1), resp
ectively. Although effective and safe in adult patients, we recommend cauti
on with. the use of droperidol-morphine mixtures for PCA in paediatric pati
ents.