Tetanus is a preventable disease that continues to affect people in the Uni
ted States due to poor immunization practices in our health care system. A
57-year-old man with type 2 diabetes mellitus, hypertension, and end-stage
renal disease with many hospital admissions came to the hospital emergency
department because of a blackened great toe. He denied pain in the toe or k
nowledge of foot injury. The patient also complained of temporomandibular t
enderness accompanied by inability to open his mouth completely. The man's
problems progressed to generalized tetanus and required a long hospitalizat
ion. Clostridium tetani can flourish in the anaerobic environment of a diab
etic foot infection. Practitioners should be aware of tetanus as a rare but
potentially serious complication of diabetic foot infections.