A saponin with anti-ulcerogenic effect from the flowers of Spartium junceum

A new oleanene-type saponin with potent anti-ulcerogenic activity was isola ted from the flowers of Spartium junceum. The various techniques of NMR spe ctral analysis, viz. H-1, C-13, DEFT, C-H COSY, H-H COSY, COLOC, NOESY, HMB C, HMQC, in conjunction with EI- and FAB-mass spectrometry, revealed that t he structure of the isolated saponin was 3-O-[alpha-L-rhamnopyranosyl-(1--> 2)-O-beta-D-glucopyranosyl-(1 --> 2)-beta-D-glucuronopyranosyl]-3 beta,16 beta,22 beta,24-tetrahydroxy-olean-12-ene and named as spartitrioside. (C) 1999 Published by Elsevier Science Ltd. All rights reserved.