Secondary personality change in psychiatric in-patients

Secondary personality change (SPC) can be caused by various medical conditi ons and is rarely reported. We retrospectively investigated the prevalence, characteristics, clinical features and treatment response in psychiatric i n-patients with a primary diagnosis of SPC. Ten cases of SPC were diagnosed in a series of 5774 patients. Head trauma was the leading cause of SPC. Im pulsivity, affective lability and aggression were commonly found in these S PC patients. After medication treatment, all SPC patients had mild to moder ate improvement. Secondary personality change is rarely diagnosed in psychi atric in-patients and responds poorly to medication treatment.