Bone scintigraphy and single photon emission computed tomography (SPECT) ma
y be performed for evaluation of lower back pain, especially when a bone ab
normality is suspected. Various patterns of tracer activity based on precis
e identification of the anatomic location of increased uptake may be observ
ed and used to evaluate bones and joints, Lesions centered about the disk s
pace and vertebral body include spondylodiskitis, metastatic disease, verte
bral body fracture, and degenerative disease (disk disease, spondylosis def
ormans). In diskitis, tracer uptake has a vertical orientation. Metastatic
involvement should be suspected in solitary lesions evaluated with SPECT wh
en the area of increased uptake extends from the vertebral body into the pe
dicle, Fractures are seen on planar and SPECT images as a linear, horizonta
lly oriented area of increased uptake centered in the vertebral body, In de
generative disease, increased uptake is centered about the disk space and m
ay be seen in and project beyond the surface of the vertebral body. Lesions
of the posterior arch (comprising the pedicle, lamina, and facet joints) i
nclude spondylolysis, pedicle lesions, osteoarthritis of the facet joints,
and fracture of the transverse process. Scintigraphy may help differentiate
long-standing asymptomatic spondylolysis from ongoing disease, In osteoart
hritis of the facet joints, SPECT may be used to select patients to be trea
ted with therapeutic injections. Increased uptake in the transverse process
most often indicates a fracture, although tumors may also occur in this lo
cation, These findings at planar bone scintigraphy and SPECT allow differen
tiation of common pathologic conditions and can lead to a specific diagnosi
s.