H. Inaba et al., The effect of thorough preoperative disinfection on the incidence of postoperative mediastinitis, SURG TODAY, 29(7), 1999, pp. 601-605
This study was conducted to evaluate the effectiveness of scrubbing the ski
n of patients scheduled to undergo elective cardiac surgery with disinfecta
nt solutions in an attempt to reduce the incidence of the potentially fatal
postoperative complication of mediastinitis, Since April 1991, we have rou
tinely disinfected the skin of all such patients three times preoperatively
, A retrospective comparison of the incidence of mediastinitis before and a
fter April 1991 was carried out. Microbiological examinations of the anteri
or chest were conducted in ten patients admitted for elective operations, a
nd in four patients admitted for emergency surgery. Specimens were obtained
before each scrubbing, before the operation, and just after skin closure.
There was a significant decrease in the general incidence of mediastinitis
after April 1991 (P < 0.01). Microbiologically, significant decreases in co
lony counts were also observed after the first (P < 0.05) and second scrubb
ing (P < 0.05) in the ten patients specifically studied before elective sur
gery. No colonies grew in the postoperative specimens from any of these pat
ients, but colony formations were observed in two of the four patients who
underwent emergency surgery (P = 0.066), Thus, we conclude that our thoroug
h disinfection method effectively achieves adequate, prolonged suppression
of the skin flora, which explains the marked decrease in the incidence of m
ediastinitis in our hospital since its institution.