Synthesis and enantiomeric excess measurements of optically active N-acetyl tetramic acids

Authors
Petroliagi, M Igglessi-Markopoulou, O
Citation
M. Petroliagi et O. Igglessi-markopoulou, Synthesis and enantiomeric excess measurements of optically active N-acetyl tetramic acids, TETRAHEDR-A, 10(10), 1999, pp. 1873-1875
Citations number
8
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
10
Issue
10
Year of publication
1999
Pages
1873 - 1875
Database
ISI
SICI code
0957-4166(19990521)10:10<1873:SAEEMO>2.0.ZU;2-C
Abstract
A facile route to chiral functionalised tetramic acids through C-acylation- cyclisation reactions of active methylene compounds with N-hydroxysuccinimi de esters of N-acetyl-L-amino acids is described. Enantiomeric excesses and physical characteristics of all compounds are reported. (C) 1999 Elsevier Science Ltd. All rights reserved.