Enantioselective copper-catalysed 1,4-addition of diethylzinc to cyclohexenone using chiral diphosphite ligands

Authors
Pamies, O Net, G Ruiz, A Claver, C
Citation
O. Pamies et al., Enantioselective copper-catalysed 1,4-addition of diethylzinc to cyclohexenone using chiral diphosphite ligands, TETRAHEDR-A, 10(10), 1999, pp. 2007-2014
Citations number
37
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
10
Issue
10
Year of publication
1999
Pages
2007 - 2014
Database
ISI
SICI code
0957-4166(19990521)10:10<2007:EC1ODT>2.0.ZU;2-J
Abstract
Bulky diphosphite ligands derived from ribo- and xylofuranose were tested i n the copper asymmetric catalytic addition of diethylzinc to 2-cyclohexenon e. The xylose derivatives provide enantiomeric excesses in the range of 22- 53%. We also describe the preparation of the ribofuranose diphosphite ligan ds. (C) 1999 Elsevier Science Ltd. All rights reserved.