G. Garratty et al., Severe immune hemolytic anemia associated with prophylactic use of cefotetan in obstetric and gynecologic procedures, AM J OBST G, 181(1), 1999, pp. 103-104
Second- and third-generation cephalosporins, especially cefotetan, are incr
easingly associated with severe, sometimes fatal immune hemolytic anemia. W
e noticed that 10 of our 35 cases of cefotetan-induced hemolytic anemias we
re in patients who had received cefotetan prophylactically for obstetric an
d gynecologic procedures. Eight of these cases of severe immune hemolytic a
nemia are described.