Peptidyl-prolyl cis-trans isomerases: Structure and functions

Authors
Pliyev, BK Gurvits, BY
Citation
Bk. Pliyev et By. Gurvits, Peptidyl-prolyl cis-trans isomerases: Structure and functions, BIOCHEM-MOS, 64(7), 1999, pp. 738-751
Citations number
141
Categorie Soggetti
Biochemistry & Biophysics
Journal title
BIOCHEMISTRY-MOSCOW
ISSN journal
00062979 → ACNP
Volume
64
Issue
7
Year of publication
1999
Pages
738 - 751
Database
ISI
SICI code
0006-2979(199907)64:7<738:PCISAF>2.0.ZU;2-G
Abstract
Peptidyl-prolyl cis-trans isomerases (PPT) catalyze cis-trans isomerization of imide bonds in peptides and proteins. This review summarizes the litera ture on the structure and functions of PPIs, their involvement in protein f olding, and organization of PPI-containing receptors and membrane channels. A possible role of several PPIs in distant interactions between cells is d iscussed.