beta-amyloid: Alzheimer's disease and brain beta-amyloidoses

This review considers some aspects of the biochemistry of beta-amyloid, a p rotein which produces insoluble deposits in the brain. These deposits are a specific morphological feature of Alzheimer's disease, Down's syndrome, an d senile dementia. Our contribution. to the concept of a soluble form of be ta-amyloid as of a normal human protein is presented.