Antiallergic agent from natural sources. 2. Structures and leukotriene release-inhibitory effect of torososide B and torosachrysone 8-O-6 ''-malonyl beta-gentiobioside from Cassia torosa CAV.
M. Kanno et al., Antiallergic agent from natural sources. 2. Structures and leukotriene release-inhibitory effect of torososide B and torosachrysone 8-O-6 ''-malonyl beta-gentiobioside from Cassia torosa CAV., CHEM PHARM, 47(7), 1999, pp. 915-918
Two new anti-allergic compounds, torososide B and torosachrysone 8-O-6 "-ma
lonyl gentiobioside were isolated from the seeds of Cassia torosa CAV., and
their structures were established as physcion 8-O-beta-D-glucopyranosyl-(1
-->6)-beta-D-glucopyranosyl-(1-->3)-beta-D-glucopyranosyl-( 1-->6)-beta-D-g
lucopyranoside and torosachrysone 8-O-beta-D-glucopyranosyl-(1-->6)-6-malon
yl po-glucopyranoside on the basis of spectral and chemical evidence.
Torososide B and torosachrysone 8-O-6 "-malonyl gentiobioside were found to
inhibit the release of leucotrienes from rat peritoneal mast cells induced
by calcium ionophore A 23187.