New hexahydrocarbazoles and spiro indoles, and their affinity for D-2 dopamine and 5-HT2A serotonin receptors

Authors
Fernandez, F Garcia-Mera, X Rodriguez, G Urrutia, A
Citation
F. Fernandez et al., New hexahydrocarbazoles and spiro indoles, and their affinity for D-2 dopamine and 5-HT2A serotonin receptors, CHEM PHARM, 47(7), 1999, pp. 1006-1009
Citations number
16
Categorie Soggetti
Chemistry & Analysis
Journal title
CHEMICAL & PHARMACEUTICAL BULLETIN
ISSN journal
00092363 → ACNP
Volume
47
Issue
7
Year of publication
1999
Pages
1006 - 1009
Database
ISI
SICI code
0009-2363(199907)47:7<1006:NHASIA>2.0.ZU;2-Z
Abstract
In a search for novel atypical antipsychotics, the synthesis of new hexahyd rocarbazoles and spiro indoles N-substituted with a 3-(dimethylamino)propyl chain is described, together with the results of an in vitro evaluation of their affinities for D-2 and 5-HT2A receptors.