Ticks are capable of transmitting viruses, bacteria, protozoa, and ricketts
iae to man. Several of these tick-borne pathogens can lead to pulmonary dis
ease. Characteristic clinical Features, such as erythema migrans in Lyme di
sease, ol spotted rash in a spotted fever group disease, may serve as impor
tant diagnostic clues. Successful management of tick-borne diseases depends
on a high index of suspicion and recognition of their clinical features. P
atients at risk for tick bites may be coinfected with two or more tick-born
e pathogens, A Lyme vaccine has recently become available for use in the Un
ited States, Disease prevention depends on the avoidance of tick bites. Whe
n patients present with respiratory symptoms and a history of a recent tick
bite or a characteristic skin rash, a differential diagnosis of a tick-bor
ne pulmonary disease should be considered, Early diagnosis and appropriate
antibiotic therapy for these disorders lead to greatly improved outcomes.