Citation
M. Yuan et al., Study on the crystal structure of RS-1-(2-methoxyphenyl)-4-[3-(1-naphthyloxy)-2-hydroxypropyl]-piperazine, CHIN J ST C, 18(4), 1999, pp. 315-316
Citations number
3
Categorie Soggetti
Inorganic & Nuclear Chemistry
Journal title
CHINESE JOURNAL OF STRUCTURAL CHEMISTRY
ISSN journal
02545861
→ ACNP
Volume
18
Issue
4
Year of publication
1999
Pages
315 - 316
Database
ISI
SICI code
0254-5861(1999)18:4<315:SOTCSO>2.0.ZU;2-F
Abstract
In order to confirm the existence and the position of the hydroxy group in
the RS-1-(2-methoxyphenyl)-4-[3-(1-naphthyloxy)-2-hydroxypropyl]-piperazine
(C24H28N2O3) molecule, which is found to be a selective antagonist against
postsynaptie membrane alpha(1) receptor, its crystal structure has been de
termined by X-ray diffraction analysis. The crystal belongs to the triclini
c system: and the space group is P (1) over bar, with a=7.375(2), b=11.733(
2), c=12.402(2) Angstrom, alpha=91.68(2), beta=101.31 (3), gamma=95.40(2)de
grees, V=1046.4(4) Angstrom(3), Z=2, D-c=1.246 g/cm(3). Final R-f=0.076.