Stereochemical resolution of racemates, in HPLC, using a chiral stationaryphase based upon immobilized alpha-chymotrypsin. II. Enzyme chiral separations

Authors
Felix, G Descorps, V
Citation
G. Felix et V. Descorps, Stereochemical resolution of racemates, in HPLC, using a chiral stationaryphase based upon immobilized alpha-chymotrypsin. II. Enzyme chiral separations, CHROMATOGR, 49(11-12), 1999, pp. 606-614
Citations number
26
Categorie Soggetti
Chemistry & Analysis","Spectroscopy /Instrumentation/Analytical Sciences
Journal title
CHROMATOGRAPHIA
ISSN journal
00095893 → ACNP
Volume
49
Issue
11-12
Year of publication
1999
Pages
606 - 614
Database
ISI
SICI code
0009-5893(199906)49:11-12<606:SRORIH>2.0.ZU;2-N
Abstract
Several racemates has been resolved according to an enzymatic recognition m echanism on an alpha-chymotrypsin chiral stationary phase. The loadability of the ACHT-CSP has been evaluated both in buffered and non-buffered mobile phases under the enzymatic process and compared with the loading capacity obtained by the structural recognition process.