Background-Circannual variation in blood pressure and in the incidence of a
cute myocardial infarction is well known but has not been investigated in c
hronic heart failure. This report describes and compares the seasonal varia
tion of chronic heart failure hospitalizations and mortality in the French
population.
Methods and Results-All deaths that occurred among French adults over the p
eriod 1992 to 1996 (n=138 602) and all discharges by adults in French publi
c hospitals for chronic heart failure over the period 1995 to 1997 (n=324 0
13) were examined retrospectively. First, chronic heart failure deaths in F
rance occurred with a striking annual periodicity and peaked in winter (Dec
ember through January), both in the overall population and in subgroups def
ined by age (>44 years old) and sex. The distribution of cumulative monthly
deaths differed by nearly 35%, ranging from a peak of 20% above average in
January to 15% below average in August (Roger's test: P<0.001). Second, ho
spitalizations for chronic heart failure in French public hospitals followe
d a similar seasonal pattern (P<0.001), with a winter-spring predominance (
+7% to +10% from December through April). Third, for persons greater than o
r equal to 85 years old, excess hospitalizations occurred earlier in the ye
ar, with marked synchronized peaks in January for both mortality and hospit
alizations (P<0.001).
Conclusions-Clear seasonal variations in adult chronic heart failure hospit
alizations and deaths were identified. The considerable economic impact on
health care services warrants further epidemiological investigations and a
more comprehensive approach to disease management.