Borderline hypertension is a widespread condition and because of its large
prevalence, it has a major impact on the cardiovascular mortality of the po
pulation. A modest elevation of blood pressure in borderline hypertension i
s closely associated with multiple theologic, hemodynamic, humoral and meta
bolic abnormalities. Many of these abnormalities, independently of the bloo
d pressure, increase the coronary risk in patients with borderline hyperten
sion.
There is no sufficient evidence in the literature to propose a well structu
red algorithm of management and treatment of borderline hypertension.
Establishing a reliable baseline blood pressure (by ambulatory or home bloo
d pressure monitoring) is the first step in the management of borderline hy
pertension. One year of intensive nonpharmacologic treatment is recommended
as the first therapeutic modality. If this fails to decrease the blood pre
ssure, pharmacologic treatment with small doses of antihypertensive medicat
ion is recommended in patients with dyslipidemia or in patients whose out o
f office blood pressure remains elevated.