Let R be a discrete valuation ring and G a finite group. Let alpha : G x G
--> R\{0} be a generalized 2-cocycle, i.e. not necessarily taking its value
s in the units of R, and consider the generalized twisted group ring R *(al
pha) G. In this paper we derive a criterion for R *(alpha) G to be separabl
e over its center. This leads us to study the center and the prime ideals o
f R *(alpha) G. Furthermore, we give some results on indecomposable modules
over R *(alpha) G.