Use of a plastic insulin dosage guide to correct blood glucose levels out of the target range and for carbohydrate counting in subjects with type 1 diabetes

OBJECTIVE - To improve glycemic control, a hand-held plastic Insulin Dosage Guide was developed to correct blood glucose levels outside of the target range. RESEARCH DESIGN AND METHODS - Protocol 1: Some 40 children (mean age 10.6 /- 4.6 years) were randomly assigned for 3 months to use a written-on-paper algorithm or the Insulin Dosage Guide to correct abnormal blood glucose le vels. Mean HbA(1c) and blood glucose levels and time to teach insulin dosag e correction were compared. Protocol 2: The Insulin Dosage Guide was used b y 83 subjects (mean age 11.4 +/- 4.3 years) for 1 year, and mean HbA(1c) le vels, blood glucose levels, and number of consecutive high blood glucose va lues taken before and after the year were compared. Protocol 3: Some 20 pat ients (mean age 10.1 +/- 3.7 years) using rapid-acting insulin and 64 patie nts (mean age 15.9 +/- 3.6 years) using an insulin pump and rapid-acting in sulin used the Insulin Dosage Guide and had mean blood glucose levels, HMI, , and percentage of blood glucose levels outside of the target range determ ined. RESULTS - Protocol 1: There was a significant reduction in mean HbA(1c) (P = 0.04) and blood glucose levels (P = 0.05) and in the time needed to teach how to correct blood glucose values using the Insulin Dosage Guide compare d with the paper algorithm. Protocol 2: There was a decrease in mean HbA(1c ) levels (P = 0.0001) and a decrease in the mean number of consecutive bloo d glucose levels (P = 0.001) over the 1-year time period. Protocol 3: With rapid-acting insulin, there was a significant increase in the percentage of blood glucose levels within the target range (1 month, P = 0.04; at 3 mont hs, P = 0.03). With the insulin pump, there was a high rate (90%) of blood glucose levels in the target range during pump initiation when the Insulin Dosage Guide was used. CONCLUSIONS - This inexpensive hand-held plastic card, which is portable an d easy to use, may help patients improve glycemia and successfully manage d iabetes.