Drug injection and syringe sharing is common among IDUs in prison, As a con
sequence, the prevalence of blood-borne viral infections is several-fold hi
gher in prison than in the corresponding communities. Prisoners have been d
enied access to syringe exchange programmes, even though they have been pro
ven to be highly effective in community settings. A 12-month harm reduction
programme which included syringe exchange was introduced into the only fem
ale prison (Hindelbank) in Switzerland, The programme was studied for 12 mo
nths (pilot phase). After the programme was completed, there was follow-up
12 months later (follow-up phase). Baseline data were collected on 137 of 1
61 prisoners. Follow up-data were collected on 57 of 64 prisoners. Particip
ants were interviewed several times about their use and injection of drugs
and their shared use of syringes. Additional data on the number of syringes
exchanged were also collected. Reports of drug use and injection in prison
did not increase. The exchange of syringes was related to drug availabilit
y. Frequency of drug use increased in relation to duration of incarceration
. Frequency of drug use decreased the longer the project had been implement
ed. None of the main arguments raised against the introduction of syringe d
istribution into prison, such as assault or an increase in drug injecting,
was evident in this study. The results, although limited by the nature and
the size of the prison, suggest that syringe exchange has a role in the pri
son setting.