LIGHT AND ELECTRON-MICROSCOPIC EXAMINATION OF VARIOUS DOSES OF GIVEN VITAMIN-A ON THE DEVELOPMENT OF CORNEA IN MICE - PARTLY PRESENTED IN ICEM 13-PARIS

Vitamin A (0.2 mu gr, 0.6 mu gr, 1.2 mu gr) was administered orally to the mice on days 8-11 of gestation. Fetuses were removed on day 17 of gestation. No external malformation of the fetuses was seen on the st ereomicroscope investigation. Corneal degeneration was seen on the lig ht and electron microscopic examination. As a result it was accepted t hat vitamin A taken during the critical periods of gestation affected the development of cornea.