Malignant fibrous histiocytoma (MFH) of the gastrointestinal tract is a rar
e occurrence. We report a case of MFH of the rectum in a 55-year-old man. U
ltrasound examination revealed thickening of the rectal wall and the biopsy
study indicated MFH. The patient underwent abdominoperineal resection and
chemoradiation and is doing well after 46 months. A high index of suspicion
for colorectal MFH should be taken into account in order to avoid histolog
ical misdiagnosis.