A series of 2-substituted 1,3,4-isoquinolinetriones (B) 1-15, precursors of
the phthalamic acids and of the 1,3-dihydro-1-hydroxy-3-oxo-1-isobenzofura
ncarboxamides (F), possessing root antigravitropic activities, were prepare
d and evaluated for herbicidal activity on weeds and crops. Among the compo
unds examined, several derivatives were very active against weeds, in many
cases more active than the commercially available herbicides used as the re
ference standards. Phytotoxicities on crops, selectivity and persistence of
herbicidal effect were observed. (C) 1999 Elsevier Science S.A. All rights
reserved.