The process of psychological adjustment to breast cancer was examined at di
agnosis and at 3- and 6-month follow-ups in a sample of 80 women with Stage
I-Stage IV breast cancer. At diagnosis, symptoms of anxiety/depression wer
e predicted by low dispositional optimism, and this path was partially medi
ated by use of emotion-focused disengagement coping. Younger age also was p
redictive of anxiety/depression symptoms at time of diagnosis, and this rel
ationship was fully mediated by magnitude of intrusive thoughts. At 3 month
s, changes in anxiety/depression symptoms were predicted only by intrusive
thoughts. At 6 months, low dispositional optimism reemerged as a significan
t predictor of changes in anxiety/depression and again was partially mediat
ed by the use of emotion-focused disengagement coping. Independent effects
for problem-focused engagement and disengagement and emotion-focused engage
ment coping were also found at 6 months. Implications of these data for psy
chosocial interventions with breast cancer patients are highlighted.