Elevated chemokine concentrations in sera of human immunodeficiency virus (HIV)-seropositive and HIV-seronegative patients with tuberculosis: a possible role for mycobacterial lipoarabinomannan
Np. Juffermans et al., Elevated chemokine concentrations in sera of human immunodeficiency virus (HIV)-seropositive and HIV-seronegative patients with tuberculosis: a possible role for mycobacterial lipoarabinomannan, INFEC IMMUN, 67(8), 1999, pp. 4295-4297
Levels of interleukin 8 (IL-8), gamma interferon-inducible protein 10 (IP-1
0), monocyte chemoattractant protein 1 (MCP-1), and macrophage inflammatory
protein 1 beta (MIP-1 beta) were elevated in patients with tuberculosis. I
P-10 and MCP-1 levels were higher in human immunodeficiency virus (HIV)-ser
opositive patients than in HIV-seronegative patients with tuberculosis. Lip
oarabinomannan induced IL-8, MCP-1, and MIP-1 beta in vitro, which was part
ly inhibited by anti-tumor necrosis factor antibody.