Elevated chemokine concentrations in sera of human immunodeficiency virus (HIV)-seropositive and HIV-seronegative patients with tuberculosis: a possible role for mycobacterial lipoarabinomannan

Citation
Np. Juffermans et al., Elevated chemokine concentrations in sera of human immunodeficiency virus (HIV)-seropositive and HIV-seronegative patients with tuberculosis: a possible role for mycobacterial lipoarabinomannan, INFEC IMMUN, 67(8), 1999, pp. 4295-4297
Citations number
17
Categorie Soggetti
Immunology
Journal title
INFECTION AND IMMUNITY
ISSN journal
00199567 → ACNP
Volume
67
Issue
8
Year of publication
1999
Pages
4295 - 4297
Database
ISI
SICI code
0019-9567(199908)67:8<4295:ECCISO>2.0.ZU;2-1
Abstract
Levels of interleukin 8 (IL-8), gamma interferon-inducible protein 10 (IP-1 0), monocyte chemoattractant protein 1 (MCP-1), and macrophage inflammatory protein 1 beta (MIP-1 beta) were elevated in patients with tuberculosis. I P-10 and MCP-1 levels were higher in human immunodeficiency virus (HIV)-ser opositive patients than in HIV-seronegative patients with tuberculosis. Lip oarabinomannan induced IL-8, MCP-1, and MIP-1 beta in vitro, which was part ly inhibited by anti-tumor necrosis factor antibody.