An experimental study of the spontaneous aggregation geometry of siali
c acid containing glyco-lipids, the gangliosides, in water solution is
presented. Interestingly enough, it is possible to follow the transit
ion from the energetically ''Frustrated'' bilayer type structures of p
ure GM3 solutions to lower energy vesicular states and then to mixed m
icellar solutions by progressively adding the second ganglioside GMI t
o the initial GM3 solution. (C) 1997 Elsevier Science B.V.