Diagnostic value of anti-hepatitis C virus (HCV) core immunoglobulin M in recurrence of HCV infection after orthotopic liver transplantation

Authors
Casino, C Lilli, D Rivanera, D Comanducci, A Rossi, M Casciaro, G Pecorella, I Alfani, D Mancini, C
Citation
C. Casino et al., Diagnostic value of anti-hepatitis C virus (HCV) core immunoglobulin M in recurrence of HCV infection after orthotopic liver transplantation, J CLIN MICR, 37(8), 1999, pp. 2726-2728
Citations number
23
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Microbiology
Journal title
JOURNAL OF CLINICAL MICROBIOLOGY
ISSN journal
00951137 → ACNP
Volume
37
Issue
8
Year of publication
1999
Pages
2726 - 2728
Database
ISI
SICI code
0095-1137(199908)37:8<2726:DVOACV>2.0.ZU;2-G
Abstract
The significance of anti-hepatitis C virus (HCV) core immunoglobulin M (IgM ) and its relationship with genotypes, alanine aminotransferase abnormality , and histological data were studied for 18 patients who had undergone orth otopic liver transplantation due to HCV-related end-stage disease. During f ellow-up, IgM response seemed to be associated with the recurrence of HCV i nfection but did not correlate with abnormal alanine aminotransferase level s and histological data. In addition, the results of this study indicated t hat the detection of HCV RNA is critical for diagnosis of reinfection in li ver transplantation.